Evaluation of Angiogenesis Assays

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A Review on Angiogenesis and Its Assays

Angiogenesis or formation of new blood vessels from preexisting vasculature is a key process in some physiological conditions such as wound healing, growth, and action of female reproductive organs. Moreover, disturbance of the mechanisms of physiological angiogenesis has a role in pathogenesis of some diseases in the form of overproliferation of blood vessels such as cancers, psoriasis, arthri...

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a review on angiogenesis and its assays

angiogenesis or formation of new blood vessels from preexisting vasculature is a key process in some physiological conditions such as wound healing, growth, and action of female reproductive organs. moreover, disturbance of the mechanisms of physiological angiogenesis has a role in pathogenesis of some diseases in the form of overproliferation of blood vessels such as cancers, psoriasis, arthri...

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Angiogenesis assays: a critical overview.

BACKGROUND Angiogenesis, the formation of new blood vessels, is an integral part of both normal developmental processes and numerous pathologies, ranging from tumor growth and metastasis to inflammation and ocular disease. Angiogenesis assays are used to test efficacy of both pro- and antiangiogenic agents. METHODS Most studies of angiogenesis inducers and inhibitors rely on various models, b...

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A Review on Angiogenesis Assays

The angiogenesis activity was involved in many physiological and pathological conditions. The research on angiogenesis activity was increased and many new methods are come for the evaluation of the angiogenesis activity. Previously Robert Auerbach et al., described the methods used for the evaluation of angiogenesis activity. We added some more techniques to that which are currently used for th...

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A brief history of angiogenesis assays.

The major problem with angiogenesis research is the choice of an appropriate assay. Currently, many in vitro and in vivo techniques are available for research into the functions of endothelial cells during angiogenesis. In this historical review article, we describe and evaluate the methodology and specific features of some of the most frequently used of these assays.

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ژورنال

عنوان ژورنال: Biomedicines

سال: 2019

ISSN: 2227-9059

DOI: 10.3390/biomedicines7020037